Sesamin is a lignan isolated from sesame seeds. Fat can be oxidized in the mitochondria and the peroxisomes of cells, the majority of this oxidation occurring in skeletal muscle cells and the liver. PPARalpha activation by sesamin increases fat oxidation in mitochondria and peroxisomes by increasing the expression of enzymes involved in beta-oxidation of fatty acids.

What the ultimate fat burning blend? Try combining 100g of Sesamin, 100g of Green Tea, 250g of Hydroxy Citric Acid, 250g of Acetyl Carnitine and 10g of Caffeine. The result will be 200 doses of fat burner far more potent than anything available off the shelf.

Sesamin supplementation has also been shown to decrease lipogenesis (fat storage) by decreasing lipogenic enzymes in the liver as well as that Sesamin has been shown to increase ketone production which should aid muscle sparing when dieting.

In short, Sesamin can increase thermogenesis, increase fat oxidisation, decrease fat storage, increase insulin sensitivity, increase ketone formation, spare glucose, increase Hdl, lower ldl, improve liver effect while producing no stimulant effect.

For best results a dosage of 500mg to 1g two to three times a day is suggested. It is advised to take Sesamin with food.