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What are NMN Supplements?

What are NMN Supplements?

What is NMN, and what is it good for?

So, what are NMN supplements, and what can they bring to the table?

Firstly, what is NMN?

NMN, or Nicotinamide Mononucleotide, is a naturally occurring compound that plays an important role in the production of NAD+ (nicotinamide adenine dinucleotide). NAD+ is a vital molecule in cells that helps produce energy.

As we age, our NAD+ levels tend to decline. This leads to less cell energy and slower repairs.

This is where NMN steps in. NMN can boost these NAD+ levels, giving our cells a much-needed pick-me-up.

Fitness enthusiasts, take note! Higher NAD+ can mean better muscle work and stamina. Research even points to NMN aiding in boosting energy metabolism.

A study released in 2021 examined the impact taking NMN had on amateur runners during training. 48 runners aged between 27 and 40 took either 300mg, 600mg or 1200mg per day for 6 weeks, with some taking a placebo. At the end of the trial, those who took NMN saw increased capacity, with the highest doses producing greater results.

So, if you're looking to break your personal record or just feel more energised, NMN might be your secret weapon.

Beyond fitness gains, NMN could be your fountain of youth in a capsule, thanks to its potential anti-aging effects. That’s right, NMN may slow the ageing process by elevating NAD+ levels, with research suggesting people with age-related conditions, like liver diseases, may have lower levels of NMN. More scientific research is underway to see the difference taking NMN supplements can have on NMN levels in the blood and its anti-aging effects - and it's looking promising!

Higher levels of NAD+ have also been linked to reducing the risk of heart disease, improve aging muscles by improving strength and endurance, and even helping to adjust your internal clock - meaning an NMN supplement has the potential to help you beat jet lag!

However, like all supplements, NMN isn’t one-size-fits-all. Be sure to chat with a healthcare professional before adding it to your routine.

NMN supports energy and vitality

What are the side effects of NMN Supplements?

NMN supplements are the latest craze in the health and fitness world. With all the buzz, it's no surprise that everyone's playing detective and looking for potential side effects.

While many tolerate NMN well, some have reported side effects like skin flushing, dizziness, nausea, fatigue, and headaches.

As with any supplement, it's essential to reach out to a healthcare professional before taking it. This is especially important for those with pre-existing medical conditions or those on medications.

What are the alternatives to NMN Supplements? How to increase NMN naturally

If you prefer to do things the old-fashioned way, luckily for you, you can ramp up your NMN without the pop-and-swallow routine.

Healthy Diet

Think of foods like edamame, broccoli, and avocado as your delicious NMN power trio. However, it’s important to note that even if you were to consume these foods in large quantities, the amount of NMN you'd intake would still be relatively small compared to supplements.

Broccoli is a great food


Endurance sports are another natural NMN booster. Picture this: You’re cruising on a track, not just toning those muscles but also naturally upping that NMN. Pretty cool, right?

Those are a few simple ways you can naturally enhance your NMN. But if you’re aiming to boost your NMN intake substantially, supplements are currently the most feasible way to do so.

Is an NMN Supplement safe?

NMN is believed to boost levels of NAD+, which is a coenzyme vital to cellular health and energy production.

As for its safety profile, NMN is generally well-tolerated with no severe side effects when taken at recommended dosages.

Touch base with a healthcare professional before adding any supplement to your routine, especially if you have underlying health conditions or are on medications.

So, what are NMN Supplements?

Answer: The Health Kick You Need!

NMN supplements are a promising contender for those after a performance boost or youthful glow.

In a nutshell, NMN plays an important role in our cellular machinery, affecting everything from energy metabolism to DNA repair.

Research shows that NMN may help enhance physical performance and even turn back the clock.

If you want to give this supplement a go, as always, be sure to consult a healthcare professional before use. Stay curious, stay healthy!

What are your thoughts on NMN supplements?

If you’re unsure if this supplement is right for you, contact us today. We’re always happy to answer your questions.

Nick Telesca - Technical Support Officer at Bulk Nutrients

Nick Telesca

Nick is Bulk's Customer Service team's Technical Support Officer.

Which is our way of saying he's the guy whose job it is to answer your obscenely technical supplement questions.

More about Nick Telesca


  1. Nichola J. Conlon, Ph.D, The Role of NAD+ in Regenerative Medicine, Published online 2021 Sep 28. doi: 10.1097/PRS.0000000000009673.
  2. Michelle F. Goody and Clarissa A. Henry, A need for NAD+ in muscle development, homeostasis, and aging, Published online 2018 Mar 7. doi: 10.1186/s13395-018-0154-1.
  3. Christopher Shade, PhD, The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule, 2020 Feb.
  4. Harshani Nadeeshani, Jinyao Li, Tianlei Ying, Baohong Zhang, and Jun Lu, Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns, Published online 2021 Aug 11. doi: 10.1016/j.jare.2021.08.003.
  5. Jing She, Rui Sheng, and Zheng-Hong Qin, Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors, Published online 2021 Dec 1. doi: 10.14336/AD.2021.0523.
  6. Roldan M. de Guia, Marianne Agerholm, Thomas S. Nielsen, Leslie A. Consitt, Ditte Søgaard, Jørn W. Helge, Steen Larsen, Josef Brandauer, Joseph A. Houmard, and Jonas T. Treebak, Aerobic and resistance exercise training reverses age‐dependent decline in NAD+ salvage capacity in human skeletal muscle, Published online 2019 Jun 17. doi: 10.14814/phy2.14139.
  7. Okabe, K., Yaku, K., Tobe, K. and Nakagawa, T. (2019). Implications of altered NAD metabolism in metabolic disorders. Journal of Biomedical Science, 26(1). doi:
  8. Picciotto, N.E., Gano, L.B., Johnson, L.C., Martens, C.R., Sindler, A.L., Mills, K.F., Imai, S. and Seals, D.R. (2016). Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell, 15(3), pp.522–530. doi:
  9. ‌Frederick, D.W., Loro, E., Liu, L., Davila, A., Chellappa, K., Silverman, I.M., Quinn, W.J., Gosai, S.J., Tichy, E.D., Davis, J.G., Mourkioti, F., Gregory, B.D., Dellinger, R.W., Redpath, P., Migaud, M.E., Nakamaru-Ogiso, E., Rabinowitz, J.D., Khurana, T.S. and Baur, J.A. (2016). Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metabolism, [online] 24(2), pp.269–282. doi:
  10. ‌Nakahata, Y. and Bessho, Y. (2016). The Circadian NAD+Metabolism: Impact on Chromatin Remodeling and Aging. BioMed Research International, 2016, pp.1–7. doi:
  11. ‌Liao, B., Zhao, Y., Wang, D., Zhang, X., Hao, X. and Hu, M. (2021). Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. Journal of the International Society of Sports Nutrition, 18(1). doi:

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