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Less is More? Meet Creatine Nitrate!

Less is More? Meet Creatine Nitrate!

Creatine and nitrate are two great ingredients to include in your supplement routine. Creatine has been a must-use supplement for decades and is one of the most scientifically researched supplements on the market.

Let’s begin with the basics, namely...

What is Creatine?

Creatine is a supplement that can help users gain strength and increase muscle volume due to its role in restoring ATP levels.

Nick our Technical Support Officer has a great blog post all about the benefits of creatine, how to use creatine, and creatine research.

There are different ways you can take creatine, including in powder or capsule form, and there’s also a lot of online discourse around cycling creatine for muscle building benefits – learn more here.

What is Nitrate?

Nitrates are molecules of nitrogen and oxygen found naturally in the air around us, soil, water, and some foods. Nitrate is a polyatomic ion; salts containing this ion are called nitrates. Almost all inorganic nitrates are soluble in water.

When dietary nitrates are consumed, they are reduced to nitric oxide in the body, widening blood vessels and helping blood to flow.

A review of 72 clinical studies found nitrate supplements were beneficial for time to exhaustion and improved power output, with another study finding supplementing nitrate was beneficial for maximising muscle power.

Combined, Creatine and Nitrate as Creatine Nitrate is up to ten times more soluble than Creatine Monohydrate, meaning less is needed.

Helena Sly loading a bar in the gym

What are the benefits of Creatine Nitrate?

Given Creatine Nitrate is a combination of Creatine and Nitrate, there’s no surprise the benefits of Creatine Nitrate are like Creatine Monohydrate.

Two studies examined groups using different doses of creatine nitrate supplements for weight lifting and measured their performance. Scientists saw improvements in the volume people were able to bench press, as well as improvements in their power and velocity—aka, they were able to lift more weight with more power and speed. Further research suggests pre workout containing creatine nitrate has work-producing value when it comes to bench presses during training.

The combination of creatine and nitrate adds extra physiological benefits for exercise. Because nitrates can be reduced to form nitric oxide, it’s been shown to help reduce oxygen depletion, increase exercise tolerance, and improve muscle efficiency. Creatine nitrate may give you a slightly better pump because it has a 100% absorption rate due to the nitrate, compared with creatine monohydrate’s 98% absorption rate.

Is Creatine Nitrate safe?

Researchsays yes! Creatine Nitrate is a relatively new form of supplementing creatine, but studies have shown similar benefits and safety to creatine monohydrate.One study showed that supplementation of creatine nitrate over 28 days was safe.

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References:

  1. Gao, C., Gupta, S., Adli, T., Hou, W., Coolsaet, R., Hayes, A., Kim, K., Pandey, A., Gordon, J., Chahil, G., Belley-Cote, E.P. and Whitlock, R.P. (2021). The effects of dietary nitrate supplementation on endurance exercise performance and cardiorespiratory measures in healthy adults: a systematic review and meta-analysis. Journal of the International Society of Sports Nutrition, 18(1). doi: https://doi.org/10.1186/s12970-021-00450-4.
  2. ‌Coggan, A.R., Baranauskas, M.N., Hinrichs, R.J., Liu, Z. and Carter, S.J. (2021). Effect of dietary nitrate on human muscle power: a systematic review and individual participant data meta-analysis. Journal of the International Society of Sports Nutrition, 18(1). doi: https://doi.org/10.1186/s12970-021-00463-z.
  3. Joy, J.M., Lowery, R.P., Falcone, P.H., Mosman, M.M., Vogel, R.M., Carson, L.R., Tai, C.-Y., Choate, D., Kimber, D., Ormes, J.A., Wilson, J.M. and Moon, J.R. (2014). 28 days of creatine nitrate supplementation is apparently safe in healthy individuals. Journal of the International Society of Sports Nutrition, 11(1). doi: https://doi.org/10.1186/s12970-014-0060-9.
  4. Galvan, E., Walker, D.K., Simbo, S.Y., Dalton, R., Levers, K., O’Connor, A., Goodenough, C., Barringer, N.D., Greenwood, M., Rasmussen, C., Smith, S.B., Riechman, S.E., Fluckey, J.D., Murano, P.S., Earnest, C.P. and Kreider, R.B. (2016). Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance. Journal of the International Society of Sports Nutrition, [online] 13(1), p.12. doi: https://doi.org/10.1186/s12970-016-0124-0.
  5. Jäger, R., Purpura, M., Shao, A., Inoue, T. and Kreider, R.B. (2011). Analysis of the efficacy, safety, and regulatory status of novel forms of creatine. Amino Acids, [online] 40(5), pp.1369–1383. doi: https://doi.org/10.1007/s00726-011-0874-6.
  6. ‌Galvan, E., O’Connor, A., Goodenough, Y.C., Dalton, R., Levers, K., Barringer, N., Cho, M., Jung, P., Greenwoord, M., Rasmussen, C., Murano, P.S., Earnest, C.P. and Kreider, R. (2015). Effects of 28 days of two creatine nitrate based dietary supplements on bench press power in recreationally active males. Journal of the International Society of Sports Nutrition, [online] 12(Suppl 1), p.P17. doi: https://doi.org/10.1186/1550-2783-12-S1-P17.

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