Laxogenin is a plant based hormone which is isolated from the smilax sieboldii plant, a species common to China and Japan.
First isolated in 1992 it is considered a steroidal sapogenin similar to Tribulus, however it is proven to be much more effective.
The active ingredients Brassinosteroids are said to be responsible for the muscle building and strength properties, having a positive effect on lean muscle growth, by increasing protein synthesis and inhibiting muscle breakdown.
Bulk Nutrients' Laxogenin Capsules are blended with Phosphatidylcholine to enhance absorption and uptake, with each capsule containing 25mg of Laxogenin and 100mg of Phosphatidylcholine.
A typical dose of Laxogenin is 50 - 100mg (2 - 4 capsules per day).
This dose is based on a man of average weight.
For best results we recommend cycling off the product for a period after 4 - 6 weeks of continual dosing.
Polydextrose, Phosphatidylcholine, Laxogenin.
Capsules contain gelatin.
What is Laxogenin?
Laxogenin is a sapogenin, a natural anabolic agent which is derived from the plant smilax siboldii. It is said to have similar effects to anabolic compounds, however, Laxogenin is natural and is not liver toxic.
It is primarily taken to improve strength and increase muscle volume, as well as to increase recovery effects after training.
What is a typical dose of Laxogenin?
A standard dose is approx. 100mg, which is 4 x 25mg capsules of the Bulk Nutrients product. Some people use lower doses, while others prefer higher doses. Dosing around 200mg has been reported to cause headaches, which is why doses around 100mg are recommended.
How does laxogenin work in the body?
Laxogenin is said to work by promoting lipolysis by binding to the androgen receptor. By enhancing triiodothyronine (T3) and reducing thyroid binding globulin. The closet evidence for Laxogenins effectiveness is a study done on rats using the brassinosteroid, 28-Homobrassinolide (HB). The results were that it stimulated protein synthesis and inhibited protein degradation.
Notably, the study showed positive effects with no androgenic side effects.
What kind of real world benefits can I expect?
Recovery from injury may well be faster
Strength will be improved, in a similar way to using a product such as creatine
Which people should / shouldn’t use Laxogein?
Competitive “natural” athletes should be great responders to laxogenin
Athletes who are suffering from injury could use laxogenin during the recovery process.
While still useful for women, men seem to respond better to laxogenin due to the effects of testosterone on brassinosteroids. Higher testosterone levels seem to further enhance its benefits. This is backed up by some women being virtually “non responders”.
Is Laxogenin ok for drug tested / natural athletes?
Laxogenin is not on any WADA / ASADA prohibited substance lists as of 2016. Laxogenin does not raise testosterone so it is very unlikely it could trigger a failed test due to hormonal level changes.
What about absorption, is this a problem with Laxogenin?
Laxogenin appears to have some issues with absorption, which can be countered one of two ways. The first is by transdermal absorption (applying it to the skin as a lotion) the other when combined with another compound, such as phosphatidylcholine which can assist absorption.
At Bulk Nutrients, we have included phosphatidylcholine at 100mg per capsule alongside 25mg of laxogenin to increase absorption.
What time of the day should I use Laxogenin?
There is no right or wrong time of the day to take Laxogenin, the most important thing is using it daily, so don’t skip doses. If doses are missed, we do not recommend extra is consumed.
Can I take Laxogenin with other supplements?
Laxogenin is fine to use with other supplements such as Creatine, Glutamine, Protein etc. It is logical that Laxogenin would be even more effective when combined with products such as Testosterone boosters, as anecdotal reports suggest effects seem to be greater when testosterone levels are higher (hence why men are better responders).
Does Laxogenin require cycling?
Studies on rats using 28-Homobrassinolide showed that no androgenic side effects were recorded, and that hormonal levels are not affected. Anecdotal reports of Laxogenin suggest that many people find optimum benefits when cycles between 8 – 10 weeks are run. An “off” period of 4 – 6 weeks would then follow.
How do I know that Bulk Nutrients Laxogenin is real?
Laxogenin is an extremely expensive compound, one that we pay a lot of money for. We purchase laxogenin from our very trusted supplier (who we have dealt with for over 5 years and supplies us with millions of dollars’ worth of stock each year), we only receive the laxogenin after approving the laboratory reports on its purity.
Bulk Nutrients regularly tests its own compounds for purity in Australia through HPLC testing, with our ingredients having an impeccable record. We 100% guarantee the purity and potency of our laxogenin.
|Per Serve||Per 100g|
Servings Per Package: 60 (2 capsules per serve)
Serving Size: 2 Capsules
FORMULATED SUPPLEMENTARY SPORTS FOOD. NOT SUITABLE FOR CHILDREN UNDER 15 YEARS OF AGE OR PREGNANT WOMEN. SHOULD ONLY BE USED UNDER MEDICAL OR DIETIC SUPERVISION. THIS PRODUCT IS NOT A SOLE SOURCE OF NUTRITION AND SHOULD BE CONSUMED IN CONJUNCTION WITH A NUTRITIOUS DIET AND APPROPRIATE PHYSICAL TRAINING OR EXERCISE PROGRAM.
Laxogenin Capsules is regularly lab tested.
Find out more.
Posted by Donga on Sep 14, 2017
By far the best strength product I have used, far better than Tribulus and didn't get the negative side affects that I experienced with D-Aspartic Acid. Feel strong without the grumpyness of other Test Boosters. Onto my 2nd bottle taking 3 caps per day at the moment which seems to be about right for me
Posted by Amin on Jul 03, 2017
Been using it for a week, looks fine, not over the top, I have been taking 3 caps twice a day, may increase the dose and reassess
Posted by Andrew on Apr 23, 2017
I've been training for over 30 yrs and I have tried most test boosters on the market with minimal result, that was until I tried Laxogenin. I have to say this is the best one I have tried with good increases in libido ( I'm 52 so any increase is good), general well being and more energy. Hands down would definitely recommend this product to any older male looking for a boost naturally.
Posted by Shane on Jan 15, 2017
Done a full 4 week cycle. Did not notice anything as far as general feeling i.e mood, thermogenic, etc. I would say though that body fat seem to stay b reduced ion a sometimes loose diet. I did feel like i had slightly more push in the gym. Interested to see what the second cycle brings. Not sure at this stage whether i would buy again.
Posted by Chris on Dec 13, 2016
Well I've cycled off it and back on it, and now I'm assuming it's better just to go one week without and then back on. It's a great product that does wonders. Has allowed me to increase Bench and many other lifts, feeling of well being also and increased metabolism.
Posted by Anon on Nov 12, 2016
Just started a second cycle a few days ago and I'm already feeling the results.
Every body is different and reacts to supps in different ways. In the past I've tried a bunch of different test boosters based on DAA or Tribulus and no matter the brand or the dosage I would always seem to get the opposite results of what was promised, such as a huge drop in libido and feeling more anxious and weaker in the gym.
I also have a condition called Adrenal Fatigue which makes bodybuilding and the stresses of everyday life take more of a toll on my body. When I heard this product can inhibit cortisol, I was very keen to give it a try as well as being somewhat skeptical due to my previous results with test boosters.
The results I've experienced from this product are all positive. The most obvious is just feeling like a boss, which in my case means I'm standing up straighter, more energetic and confident. I feel a lot less socially awkward and have found myself having conversations with random people in the street.
I've noticed a decent increase in my appetite which has helped me to increase my daily protein and calorie intake resulting in more lean muscle.
My libido has increased.
I've found a huge increase in aggression which is great when i can channel it in the gym, I've been able to lift heavier weights and do more sets. I feel like my body is recovering a lot faster which in my case means I can do a proper workout just about everyday, something that seemed impossible with adrenal fatigue.
The increased aggression could be seen as a a problem when someone is rude to you or when you encounter idiots on the road, lucky the cops just gave me a warning haha.
I've played around with the dosage and timing a fair bit, what I found most effective for me is 4 caps first thing in the morning on an empty stomach. I'm taking it with 1 of the Bulk Nutrients Diindolylmethane cap along with my prescribed Adrenal Fatigue medication.
It probably sounds cliche but this product has changed my life and I would highly recommend it to anyone with Adrenal Fatigue.
Posted by Raz on Sep 07, 2016
Hi guys, I've been holding off writing a review as I wanted to allow it suitable time to kick in.
I've tried laxogenin before in other supplements, at mild doses, and have gotten little results.
This time around, I went with the 480 capsules, and decided to blast it at higher doses. So far I'm one tub (120 capsules) through, running it at 4 caps x 2 times daily, heres my thoughts:
Immediately, I noticed an effect on appetite gain (but not for the dirty kind of appetite gain you normally get off similar products/prohormones/test boosters etc), it is a clean appetite gain - you feel like you want to consume more protein. So I do. And that's the main benefit of this product: increased protein synthesis.
I noticed the effects immediately, within about 3 days, at such a high dose. Previously I'd only run the equivalent of 2 caps x 2 times daily. And that felt a bit mild, especially compared to the effect I get off this high a dose.
The plan is now for the 2nd tub to drop back down to 3 caps x 2 times daily, and then 2 x 2 daily for the 3rd tub, and to finally blast back up to maximum/high dose for the final tub, to maximise the gains off the $200 x 4 tubs for best value.
So far I have noticed muscle volume and a bit of strength gains - I generally feel fuller, and more pumped, for longer.
If you eat clean and train hard, I have no doubts this is a worthwhile product, particularly at higher doses. I feel like for me (~140kg bulked bodyweight at the moment) that I simply require higher doses. Smaller guys may be fine with 2-3 caps x 2 daily, which will drag out your supply a bit longer. For me though, it simply doesn't have the desired effect if I stay at such a low dose, hence why I'm cycling my doses to try and get maximum effect as well as prolong my supply as much as possible.
The capsules don't have any foul taste nor did I notice any cotton mouthy feeling. I did notice in the first tub 2 caps had been split open/torn apart and assuming wasted, but this is no real biggy and is likely to happen in any given supplement.
Posted by Dylan on Aug 31, 2016
Really great! Starting to see results
Posted by Anon on Aug 31, 2016
Haven't noticed any strength increases as of yet, however did notice an increase in thermogenic effects which I didn't expect. Possible increase in hunger. Tablets do leave a dry/cotton mouth feeling in mouth after swallowing them. Will update review once a complete cycle has been completed.