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The Natural Compound That Helps Support Healthy Joints

The Natural Compound That Helps Support Healthy Joints

Chondroitin Sulfate for Joint Pain and Chondroitin Sulfate for Osteoarthritis

Osteoarthritis sufferers have turned to supplements containing chondroitin sulfate for relief. The degenerative disease osteoarthritis wears down cartilage at the end of your bones, meaning chondroitin sulfate could have benefits for helping repair damage. Research has suggested that when taking it as a supplement, chondroitin sulfate increases the synthesis of cartilage components and prevents the breakdown of cartilage.

Several studies have shown the potential benefits of chondroitin sulfate for joint pain and function.

One research review of 26 studies showed that chondroitin supplements had benefits for improving the function of joints and pain symptoms, compared with taking a placebo. 

Chondroitin Sulfate in Clinical Trials

A review undertaken two years later suggested chondroitin sulfate may slow the progression of osteoarthritis while decreasing the need for anti-inflammatory drugs like ibuprofen. Chondroitin sulfate has been shown to create anti-inflammatory activity within the body.

Clinical trials have also shown a beneficial impact of the use of both chondroitin sulfate and glucosamine sulfate on reducing pain and increasing function while studying patients suffering from osteoarthritis in their knees.

Chondroitin Recommended Dosage

Studies show an 800mg-1200mg dosage of chondroitin sulfate each day is most effective for joint-related benefits. Considered a slow-acting supplement, chondroitin sulfate takes time to build up in the joints, which means its impact may not be seen straight away.

Researchers recommend speaking with a medical professional before adding a supplement with chondroitin sulfate into your routine, as some data suggests it may interact with some other types of medication.

Ryan Bevan Head of Operations TGA

Ryan Bevan

Ryan Bevan works hard to ensure strict TGA compliance, coordinating with external consultants, and managing intricate documentation - all while drawing strength from Bulk Nutrients' exceptional Quality Assurance team.

More about Ryan Bevan


  1. Vasiliadis, H.S. and Tsikopoulos, K. (2017). Glucosamine and chondroitin for the treatment of osteoarthritis. World Journal of Orthopedics, 8(1), p.1. doi:
  2. ‌Chen, D., Shen, J., Zhao, W., Wang, T., Han, L., Hamilton, J.L. and Im, H.-J. (2017). Osteoarthritis: toward a Comprehensive Understanding of Pathological Mechanism. Bone Research, [online] 5(1), pp.1–13. doi:
  3. ‌Jerosch, J. (2011). Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. International Journal of Rheumatology, 2011, pp.1–17. doi:
  4. ‌Zhu, X., Sang, L., Wu, D., Rong, J. and Jiang, L. (2018). Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials. Journal of Orthopaedic Surgery and Research, [online] 13(1). doi:
  5. ‌Reginster, J.-Y. and Veronese, N. (2020). Highly purified chondroitin sulfate: a literature review on clinical efficacy and pharmacoeconomic aspects in osteoarthritis treatment. Aging Clinical and Experimental Research, 33(1), pp.37–47. doi:
  6. ‌Knudsen, J.F. and Sokol, G.H. (2008). Potential Glucosamine-Warfarin Interaction Resulting in Increased International Normalized Ratio: Case Report and Review of the Literature and MedWatch Database. Pharmacotherapy, 28(4), pp.540–548. doi:
  7. ‌Reginster, J.-Y., Dudler, J., Blicharski, T. and Pavelka, K. (2017). Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis: the ChONdroitin versus CElecoxib versus Placebo Trial (CONCEPT). Annals of the Rheumatic Diseases, 76(9), pp.1537–1543. doi:
  8. ‌Martel-Pelletier, J., Kwan Tat, S. and Pelletier, J.-P. . (2010). Effects of chondroitin sulfate in the pathophysiology of the osteoarthritic joint: a narrative review. Osteoarthritis and Cartilage, 18, pp.S7–S11. doi:
  9. ‌Henrotin, Y., Marty, M. and Mobasheri, A. (2014). What is the current status of chondroitin sulfate and glucosamine for the treatment of knee osteoarthritis? Maturitas, 78(3), pp.184–187. doi:

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