Supporting Your Health: Top Supplements for GLP-1 Users

Bulk Nutrients Ambassador Selina Farrelly in the kitchen

What Are GLP-1 Medications and How Do They Work?

GLP-1 stands for glucagon-like peptide-1, a naturally occurring hormone that helps your body regulate blood sugar and appetite. GLP-1 medications (often called GLP-1 injections or weight loss drugs) mimic this hormone to slow digestion, boost insulin sensitivity, and signal fullness to your brain.

In plain English, they help you feel satisfied with less food, which can drive weight loss — but a smaller appetite can also mean missing out on protein, vitamins, minerals, and hydration. These are essential things your body needs to stay strong, energised, and healthy long term.

Common Side Effects of GLP-1 Medications

Like any medication, GLP-1 weight loss drugs come with a few knock-on effects. While they help many users achieve sustainable results and appetite control, they can also bring side effects worth keeping on your radar:

Reduced protein intake – Less food often means less protein, which raises the risk of muscle loss.
Lower vitamin and mineral intake – Smaller portions and limited variety may cut key nutrients.
Slower digestion – The “fullness effect” can sometimes tip into constipation, bloating, or gut discomfort.
Less fluid and electrolytes – Drinking less can increase the risk of dehydration.
Lower intake of bone-supporting nutrients – Reduced calcium and vitamin D can increase the risk of weaker bones over time.

Not everyone will experience these, but they’re common enough that a strategic supplement plan can help keep your GLP-1 journey smoother, stronger, and healthier.

How Supplements Can Support Health on GLP-1 Medications

When your appetite shrinks on GLP-1 medications, so does the chance of getting all the nutrients your body needs from diet alone. That’s where supplements for GLP-1 users can shine — not as a replacement for food, but as reinforcements that cover dietary shortfalls and keep your body resilient.

The right supplements can help you thrive while the medications do their job, from protecting muscle mass to supporting bone health, digestion, and energy.

Protein and Muscle Preservation

One of the biggest risks of appetite suppression isn’t just fat loss — it’s muscle loss. Protecting your muscles is essential for long-term health, strength, and metabolism. That’s where protein supplementation comes in. Getting enough protein while your appetite is low can be tricky, but the right supplements make it much easier.

Top protein and muscle-supporting supplements:

Whey Protein Powders – High-quality protein sources that support muscle recovery and help you hit daily protein targets. Choose Whey Protein Isolate (WPI) for a fast-digesting option, Whey Protein Concentrate (WPC) for a balanced all-rounder, or Protein Matrix+ for a blend of fast and slow release (whey + casein).
Plant Protein – Ideal if you’re dairy-free or vegan. Our Earth Protein combines rice and pea protein for a complete amino acid profile.
BCAAs or EAAs – A handy option when your appetite is low but you still want to protect lean mass and recovery.Check out BCAA Recovery or our Intra Workout, which delivers EAAs plus electrolytes.
Creatine Monohydrate – One of the most researched supplements, proven to support strength, energy, and muscle preservation during calorie restriction.
High-Protein Snacks – Protein bars, jerky, or ready-to-drink shakes make it easier to spread protein intake across the day, even when you’re not hungry.
Collagen Peptides – Not a complete protein, but great for supporting joints, tendons, skin, and connective tissue — all especially helpful during weight loss. It can even support gut health by helping maintain a healthy stomach lining.

Bulk Nutrients Ambassador Tammie Sarkozy with Collagen Protein

Bone Health and Micronutrient Supplements

Rapid weight loss can sometimes put bone health at risk, especially if your intake of calcium, vitamin D, and other key nutrients drops along the way. Smaller portions and reduced dietary variety mean supplementation is even more important. The right nutrients don’t just protect your bones — they also support energy, mood, and overall wellness.

Key bone and micronutrient supplements:

Calcium and Vitamin D – A powerhouse combo, well-documented to support bone density and strength.
Vitamin B12 – Plays a critical role in energy metabolism and mood regulation; low intake is common when calories (and food variety) are reduced.
Magnesium – Supports muscle relaxation, quality sleep, and blood sugar control. Zinc and vitamin B6 can also complement magnesium, particularly for recovery and energy metabolism.
Iron – Especially important for women or anyone cutting back on red meat; helps prevent fatigue and anaemia. The inclusion of organ meats, or organ supplements like freeze-dried beef liver, can provide a natural source of iron along with additional micronutrients.
Omega-3s –Backed by strong evidence for heart and brain health
CoQ10 – Supports cellular energy production.
Multivitamins – A catch-all safety net to help cover reduced nutrient intake.

Digestive, Liver, and Gut Health Support

Because GLP-1 medications slow digestion, they can sometimes cause constipation, bloating, or heaviness. Supporting your gut and liver with the right supplements can help you stay comfortable and absorb nutrients more efficiently.

Top digestive and gut health supplements:

Fibre supplements (psyllium husk, inulin) – Well-studied for bowel regularity and blood sugar control. They also support healthy gut bacteria. Our Tri Fibre+ combines multiple fibre sources to support digestion and microbiome health.
Probiotics – Evidence suggests probiotics can improve gut comfort and nutrient absorption, especially when digestion slows.
Digestive Enzymes – Useful if heavier meals feel uncomfortable, helping break down proteins, carbs, and fats. Our Digestive Fusion is packed with essential vitamins, minerals, probiotics, and digestive enzymes to support digestion and enhance immunity and overall wellness.
Aloe Vera or Slippery Elm – More on the emerging side, these plant-based options may help soothe the gut lining.
N-Acetylcysteine (NAC) – A powerful antioxidant that supports the liver by boosting glutathione production (your body’s master antioxidant). Early animal research also suggests benefits for gut health.

Metabolic and Energy Support

Even with steadier blood sugar, some people on GLP-1 medications notice dips in energy or fatigue. This can be linked to eating less, nutrient shifts, or changes in metabolism. Certain supplements may help support energy, though some are better studied than others:

Berberine – Sometimes called “Nature’s Ozempic,” berberine has been studied for its role in supporting healthy blood sugar levels and metabolic function.
Curcumin – The active compound in turmeric, curcumin is known for its anti-inflammatory effects and potential to support metabolic health.
Green Tea Extract – Provides a gentle boost in fat oxidation and metabolism. However, very high doses can place stress on the liver, so moderation is key.
Amarasate (Bitter Hop Extract) – An emerging ingredient currently being studied for its ability to stimulate GLP-1, curb appetite, and support healthy metabolism.

Lifestyle Considerations to Maximise Results

Supplements can fill nutrient gaps, but they work best when paired with smart lifestyle choices. Think of it this way: GLP-1 medications may drive weight loss, but your habits decide whether that loss is healthy, sustainable, and energising.

Prioritise Strength Training

While GLP-1 medications help reduce body fat, they can also increase the risk of muscle loss. That’s why strength training is one of the best lifestyle strategies to pair with supplements and protein.

Tips for preserving muscle while losing fat:

Train at least 2–3 times per week – Consistency is key; spread your sessions across the week to give muscles recovery time.
Focus on compound lifts – Moves like squats, deadlifts, lunges, presses, and rows work multiple muscles at once, building strength and supporting bone density.
Pair every workout with protein – Aim for 20–30g of quality protein per meal or snack. This fuels recovery and helps keep you fuller for longer.

Nicole Frain doing an exercises on her back

Stay Active

Movement isn’t just about burning calories — it’s about keeping your body feeling good. Light to moderate activity helps digestion, energy, and overall health. The best part? It doesn’t have to be intense.

Easy ways to stay active:

Daily movement adds up – Even walking, cycling, or stretching can improve digestion and energy levels.
Aim for 7,000–10,000 steps daily – A realistic target for most people that supports both metabolic and cardiovascular health.
Break it up – Short walks after meals aid digestion and blood sugar balance, and they’re easier to fit into a busy schedule.

Keep on Top of Hydration

A reduced sense of thirst is a common side effect of GLP-1 medications, and dehydration can worsen fatigue, headaches, constipation, and recovery. Staying on top of fluids keeps things running smoothly.

Hydration tips:

Carry a water bottle – Sip throughout the day, even if you don’t feel thirsty.
Aim for 2–3 litres daily – A good target for most adults, but adjust depending on your body size and activity level.
Add electrolytes when training – Replace sodium, potassium, and magnesium lost in sweat. Our Hydration Salts provide the ideal balance to combat heavy sweat-induced electrolyte loss.

Prioritise Sleep & Recovery

Good sleep is just as important as nutrition and exercise. Poor sleep can slow weight loss, increase cravings, and reduce recovery. Prioritising rest keeps hormones balanced and energy high.

Sleep and recovery tips:

Aim for 7–9 hours per night – Consistency matters more than perfection; set a routine bedtime if possible.
Practice good sleep hygiene – Create a bedtime routine and cut screen time before bed.
Consider L-Theanine – This amino acid may support calm focus during the day and improve sleep quality at night.

Manage Stress

Stress doesn’t just affect mood — it can also disrupt appetite regulation and fat loss. High cortisol levels can increase cravings and reduce recovery. Managing stress helps your body get the most from both GLP-1 meds and supplements.

Ways to manage stress:

Build daily calm into your routine – Yoga, meditation, deep breathing, or walking in nature can lower cortisol and improve overall wellbeing.
Don’t underestimate light activity – Even gentle movement, stretching, or time outdoors can reduce tension.
Consider adaptogens like ashwagandha – Research suggests these herbs may help the body adapt to stress and support resilience.

Safety Considerations for Supplementing on GLP-1 Medications

Supplements can be powerful allies, but a careful approach is key. If you’re using GLP-1 medications, take a thoughtful, evidence-based approach to keep things safe.

Smart supplement safety tips:

Consult professionals first – Always check with your doctor or dietitian before adding new supplements, especially if you’re on prescriptions.
Choose evidence-backed options – Stick with research-supported choices, not unproven quick fixes.
Go with trusted, tested brands – Quality matters. Reputable companies (yes, like us!) back their products with independent lab testing so you know what’s on the label is exactly what’s in the tub.
Use blood tests as a guide – Regular checks can highlight deficiencies and help tailor your supplement plan to your actual needs.

Supporting Your GLP-1 Journey

GLP-1 medications are effective tools for weight management, but they can bring side effects that chip away at long-term health if left unchecked. That’s where supplements step in. Protein protects muscle, vitamins and minerals support bones and metabolism, digestive and liver support keep things comfortable, and lifestyle strategies like training, hydration, stress management, and quality sleep help you feel your best.

Think of supplements not as shortcuts, but as seatbelts — keeping your body safe and supported while the medication drives the weight loss. With the right combination of smart nutrition, quality supplements, and healthy habits, you can maximise results, minimise risks, and ensure your slimmer self is also a stronger, healthier, and more resilient self.

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